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Biochemical Basis Underlying Sestrins’ Physiological Activities
Excessive accumulation of reactive oxygen species (ROS) and chronic activation of mechanistic target of rapamycin (mTOR) complex 1 (mTORC1) are well-characterized promoters of aging and age-associated degenerative pathologies. Sestrins, a family of highly conserved stress-inducible proteins, are imp...
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| Udgivet i: | Trends Biochem Sci |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4930368/ https://ncbi.nlm.nih.gov/pubmed/27174209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2016.04.005 |
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