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Biochemical Basis Underlying Sestrins’ Physiological Activities
Excessive accumulation of reactive oxygen species (ROS) and chronic activation of mechanistic target of rapamycin (mTOR) complex 1 (mTORC1) are well-characterized promoters of aging and age-associated degenerative pathologies. Sestrins, a family of highly conserved stress-inducible proteins, are imp...
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| Publicado no: | Trends Biochem Sci |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4930368/ https://ncbi.nlm.nih.gov/pubmed/27174209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2016.04.005 |
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