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GABA(A) Receptor Modulation by Etomidate Analogues

BACKGROUND: Etomidate is a highly potent anesthetic agent that is believed to produce hypnosis by enhancing γ-aminobutyric acid type A (GABA(A)) receptor function. We characterized the GABA(A) receptor and hypnotic potencies of etomidate analogues. We then used computational techniques to build stat...

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Dades bibliogràfiques
Publicat a:Anesthesiology
Autors principals: Pejo, Ervin, Santer, Peter, Wang, Lei, Dershwitz, Philip, Husain, S. Shaukat, Raines, Douglas E.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803471/
https://ncbi.nlm.nih.gov/pubmed/26691905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000992
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