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GABA(A) Receptor Modulation by Etomidate Analogues
BACKGROUND: Etomidate is a highly potent anesthetic agent that is believed to produce hypnosis by enhancing γ-aminobutyric acid type A (GABA(A)) receptor function. We characterized the GABA(A) receptor and hypnotic potencies of etomidate analogues. We then used computational techniques to build stat...
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| Publicado no: | Anesthesiology |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4803471/ https://ncbi.nlm.nih.gov/pubmed/26691905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000992 |
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