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Comparing and Combining Biomarkers as Principle Surrogates for Time-to-Event Clinical Endpoints
Principal surrogate endpoints are useful as targets for Phase I and II trials. In many recent trials, multiple post-randomization biomarkers are measured. However, few statistical methods exist for comparison of or combination of biomarkers as principal surrogates and none of these methods to our kn...
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| Опубликовано в: : | Stat Med |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4801510/ https://ncbi.nlm.nih.gov/pubmed/25352131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6349 |
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