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Optimizing and Evaluating Biomarker Combinations as Trial Level General Surrogates

We extend the method proposed in(1) for trial level general surrogate evaluation to allow combinations of biomarkers, and provide a procedure for finding the ‘best’ combination of biomarkers based on the absolute prediction error summary of surrogate quality. We use a non-parametric Bayesian model t...

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Bibliografiske detaljer
Udgivet i:Stat Med
Main Authors: Gabriel, Erin E, Sachs, Michael C, Daniels, Michael, Halloran, M Elizabeth
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399061/
https://ncbi.nlm.nih.gov/pubmed/30306600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.7996
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