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Comparing Biomarkers as Trial Level General Surrogates

An intermediate response measure that accurately predicts efficacy in a new setting can reduce trial cost and time to product licensure. In this paper, we define a trial level general surrogate, which is an intermediate response that can be used to accurately predict efficacy in a new setting. Metho...

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Bibliografske podrobnosti
izdano v:Biometrics
Main Authors: Gabriel, Erin E, Daniels, Michael J, Halloran, M Elizabeth
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045774/
https://ncbi.nlm.nih.gov/pubmed/27038302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/biom.12513
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