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Comparing Biomarkers as Trial Level General Surrogates
An intermediate response measure that accurately predicts efficacy in a new setting can reduce trial cost and time to product licensure. In this paper, we define a trial level general surrogate, which is an intermediate response that can be used to accurately predict efficacy in a new setting. Metho...
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| Publicado no: | Biometrics |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5045774/ https://ncbi.nlm.nih.gov/pubmed/27038302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/biom.12513 |
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