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Comparing Biomarkers as Principal Surrogate Endpoints

Recently a new definition of surrogate endpoint, the ‘principal surrogate’, was proposed based on causal associations between treatment effects on the biomarker and on the clinical endpoint. Despite its appealing interpretation, limited research has been conducted to evaluate principal surrogates, a...

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Bibliografische gegevens
Hoofdauteurs: Huang, Y., Gilbert, P. B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163011/
https://ncbi.nlm.nih.gov/pubmed/21517791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1541-0420.2011.01603.x
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