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Comparing Biomarkers as Principal Surrogate Endpoints

Recently a new definition of surrogate endpoint, the ‘principal surrogate’, was proposed based on causal associations between treatment effects on the biomarker and on the clinical endpoint. Despite its appealing interpretation, limited research has been conducted to evaluate principal surrogates, a...

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Detalles Bibliográficos
Main Authors: Huang, Y., Gilbert, P. B.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163011/
https://ncbi.nlm.nih.gov/pubmed/21517791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1541-0420.2011.01603.x
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