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Comparing Biomarkers as Principal Surrogate Endpoints
Recently a new definition of surrogate endpoint, the ‘principal surrogate’, was proposed based on causal associations between treatment effects on the biomarker and on the clinical endpoint. Despite its appealing interpretation, limited research has been conducted to evaluate principal surrogates, a...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3163011/ https://ncbi.nlm.nih.gov/pubmed/21517791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1541-0420.2011.01603.x |
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