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Evaluating Candidate Principal Surrogate Endpoints
Frangakis and Rubin (2002, Biometrics 58, 21–29) proposed a new definition of a surrogate endpoint (a “principal” surrogate) based on causal effects. We introduce an estimand for evaluating a principal surrogate, the causal effect predictiveness (CEP) surface, which quantifies how well causal treatm...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2726718/ https://ncbi.nlm.nih.gov/pubmed/18363776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1541-0420.2008.01014.x |
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