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Surrogate Endpoint Evaluation: Principal Stratification Criteria and the Prentice Definition

A common problem of interest within a randomized clinical trial is the evaluation of an inexpensive response endpoint as a valid surrogate endpoint for a clinical endpoint, where a chief purpose of a valid surrogate is to provide a way to make correct inferences on clinical treatment effects in futu...

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Veröffentlicht in:J Causal Inference
Hauptverfasser: Gilbert, Peter B., Gabriel, Erin E., Huang, Ying, Chan, Ivan S.F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692254/
https://ncbi.nlm.nih.gov/pubmed/26722639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/jci-2014-0007
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