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Evaluating principal surrogate endpoints with time-to-event data accounting for time-varying treatment efficacy

Principal surrogate (PS) endpoints are relatively inexpensive and easy to measure study outcomes that can be used to reliably predict treatment effects on clinical endpoints of interest. Few statistical methods for assessing the validity of potential PSs utilize time-to-event clinical endpoint infor...

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Detalhes bibliográficos
Main Authors: Gabriel, Erin E., Gilbert, Peter B.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944974/
https://ncbi.nlm.nih.gov/pubmed/24337534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxt055
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