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Augmented trial designs for evaluation of principal surrogates

Observation of counterfactual intermediate responses, and evaluation of them as candidate surrogates, is complicated in a standard randomized trial as half of the responses are systematically missing by design. Although some augmentation procedures exist for obtaining counterfactual responses, they...

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Detalhes bibliográficos
Publicado no:Biostatistics
Main Authors: Gabriel, Erin E., Follmann, Dean
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915608/
https://ncbi.nlm.nih.gov/pubmed/26825099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxv055
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