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Augmented Designs to Assess Immune Response in Vaccine Trials
This article introduces methods for use in vaccine clinical trials to help determine whether the immune response to a vaccine is actually causing a reduction in the infection rate. This is not easy because immune response to the (say HIV) vaccine is only observed in the HIV vaccine arm. If we knew w...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2536776/ https://ncbi.nlm.nih.gov/pubmed/17156291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1541-0420.2006.00569.x |
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