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Leukocyte integrin α(L)β(2) headpiece structures: The αI domain, the pocket for the internal ligand, and concerted movements of its loops
High-resolution crystal structures of the headpiece of lymphocyte function-associated antigen-1 (integrin α(L)β(2)) reveal how the αI domain interacts with its platform formed by the α-subunit β-propeller and β-subunit βI domains. The α(L)β(2) structures compared with α(X)β(2) structures show that t...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4801256/ https://ncbi.nlm.nih.gov/pubmed/26936951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1601379113 |
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