An orthotopic mouse model of hepatocellular carcinoma with underlying liver cirrhosis

Subcutaneous xenografts have been used for decades to study hepatocellular carcinoma (HCC). These models do not reproduce the specific pathophysiological features of HCCs, which occur in cirrhotic livers that show pronounced necroinflammation, abnormal angiogenesis and extensive fibrosis. As these f...

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Bibliografski detalji
Izdano u:Nat Protoc
Glavni autori: Reiberger, Thomas, Chen, Yunching, Ramjiawan, Rakesh R, Hato, Tai, Fan, Christopher, Samuel, Rekha, Roberge, Sylvie, Huang, Peigen, Lauwers, Gregory Y, Zhu, Andrew X, Bardeesy, Nabeel, Jain, Rakesh K, Duda, Dan G
Format: Artigo
Jezik:Inglês
Izdano: 2015
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4800979/
https://ncbi.nlm.nih.gov/pubmed/26203823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2015.080
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