An orthotopic mouse model of hepatocellular carcinoma with underlying liver cirrhosis

Subcutaneous xenografts have been used for decades to study hepatocellular carcinoma (HCC). These models do not reproduce the specific pathophysiological features of HCCs, which occur in cirrhotic livers that show pronounced necroinflammation, abnormal angiogenesis and extensive fibrosis. As these f...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Protoc
Egile Nagusiak: Reiberger, Thomas, Chen, Yunching, Ramjiawan, Rakesh R, Hato, Tai, Fan, Christopher, Samuel, Rekha, Roberge, Sylvie, Huang, Peigen, Lauwers, Gregory Y, Zhu, Andrew X, Bardeesy, Nabeel, Jain, Rakesh K, Duda, Dan G
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4800979/
https://ncbi.nlm.nih.gov/pubmed/26203823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2015.080
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