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Rationally combining anti-VEGF therapy with checkpoint inhibitors in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a fatal disease with rising incidence in the world. For advanced HCC, sorafenib, a multikinase inhibitor, is the only systemic therapy with proven survival benefits. Sorafenib is a pan-VEGF receptor inhibitor, and thus many studies have focused its antivascular effe...

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Detalhes bibliográficos
Publicado no:Immunotherapy
Main Authors: Hato, Tai, Zhu, Andrew X, Duda, Dan G
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5619018/
https://ncbi.nlm.nih.gov/pubmed/26865127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt.15.126
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