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KLF4 is essential for induction of cellular identity change and acinar-to-ductal reprograming during early pancreatic carcinogenesis
Understanding the molecular mechanisms of tumor initiation has significant impact on cancer early detection and intervention. To define the role of KLF4 in pancreatic ductal adenocarcinoma initiation, we used molecular biological analyses and mouse models of klf4 gain- and loss-of-function and mutan...
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| Publicat a: | Cancer Cell |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4794756/ https://ncbi.nlm.nih.gov/pubmed/26977883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2016.02.005 |
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