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KLF4-mediated Suppression of CD44 Signaling Negatively Impacts Pancreatic Cancer Stemness and Metastasis

KLF4 and CD44 regulate cancer cell stemness, but their precise functions and roles in metastatic progression are not well understood. In this study, we used both inducible and genetic engineering approaches to assess whether the activities of these two factors intersect in pancreatic ductal adenocar...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: YAN, YONGMIN, LI, ZHIWEI, KONG, XIANGYU, JIA, ZHILIANG, ZUO, XIANGSHENG, GAGEA, MIHAI, HUANG, SUYUN, WEI, DAOYAN, XIE, KEPING
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876033/
https://ncbi.nlm.nih.gov/pubmed/26880805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-1691
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