KLF4-mediated Suppression of CD44 Signaling Negatively Impacts Pancreatic Cancer Stemness and Metastasis

KLF4 and CD44 regulate cancer cell stemness, but their precise functions and roles in metastatic progression are not well understood. In this study, we used both inducible and genetic engineering approaches to assess whether the activities of these two factors intersect in pancreatic ductal adenocar...

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Gepubliceerd in:Cancer Res
Hoofdauteurs: YAN, YONGMIN, LI, ZHIWEI, KONG, XIANGYU, JIA, ZHILIANG, ZUO, XIANGSHENG, GAGEA, MIHAI, HUANG, SUYUN, WEI, DAOYAN, XIE, KEPING
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876033/
https://ncbi.nlm.nih.gov/pubmed/26880805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-1691
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