Merlin/NF2 Suppresses Pancreatic Tumor Growth and Metastasis by Attenuating the FOXM1-Mediated Wnt/β-catenin Signaling

Merlin, the protein encoded by the NF2 gene, is a member of the band 4.1 familly of cytoskeleton-associated proteins and functions as a tumor suppressor for many types of cancer. However, the roles and mechanism of Merlin expression in pancreatic cancer have remained unclear. In this study, we sough...

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Bibliographic Details
Published in:Cancer Res
Main Authors: Quan, Ming, Cui, Jiujie, Xia, Tian, Jia, Zhiliang, Xie, Dacheng, Wei, Daoyan, Huang, Suyun, Huang, Qian, Zheng, Shaojiang, Xie, Keping
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651817/
https://ncbi.nlm.nih.gov/pubmed/26483206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1952
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