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Activation of Vitamin D Receptor Signaling Downregulates the Expression of Nuclear FOXM1 Protein and Suppresses Pancreatic Cancer Cell Stemesss
PURPOSE: Dysregulated signaling of nuclear transcription factors vitamin D receptor (VDR) and Forkhead box M1 (FOXM1) play important roles in transformation and tumorigenesis. In this study, we sought to determine whether VDR signaling causally impacted FOXM1 signaling in and pathogenesis of pancrea...
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| Pubblicato in: | Clin Cancer Res |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4334671/ https://ncbi.nlm.nih.gov/pubmed/25501129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2437 |
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