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Activation of Vitamin D Receptor Signaling Downregulates the Expression of Nuclear FOXM1 Protein and Suppresses Pancreatic Cancer Cell Stemesss

PURPOSE: Dysregulated signaling of nuclear transcription factors vitamin D receptor (VDR) and Forkhead box M1 (FOXM1) play important roles in transformation and tumorigenesis. In this study, we sought to determine whether VDR signaling causally impacted FOXM1 signaling in and pathogenesis of pancrea...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: LI, ZHIWEI, JIA, ZHILIANG, GAO, YONG, XIE, DACHENG, WEI, DAOYAN, CUI, JIUJIE, MISHRA, LOPA, HUANG, SUYUN, ZHANG, YANQIAO, XIE, KEPING
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334671/
https://ncbi.nlm.nih.gov/pubmed/25501129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2437
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