HGF/Met and FOXM1 Form a Positive Feedback Loop and Render Pancreatic Cancer Cells Resistance to Met Inhibition and Aggressive Phenotypes

PURPOSE: Hepatocyte growth factor (HGF)/Met signaling plays critical roles in pancreatic ductal adenocarcinoma (PDA) development and progression and is considered a potential therapeutic target for this disease. However, the mechanism of aberrant activation of HGF/Met signaling and resistance to Met...

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Gepubliceerd in:Oncogene
Hoofdauteurs: Cui, Jiujie, Xia, Tian, Xie, Dacheng, Gao, Yong, Jia, Zhiliang, Wei, Daoyan, Wang, Liang, Huang, Suyun, Quan, Ming, Xie, Keping
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985506/
https://ncbi.nlm.nih.gov/pubmed/26876216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.14
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