Activation of Vitamin D Receptor Signaling Downregulates the Expression of Nuclear FOXM1 Protein and Suppresses Pancreatic Cancer Cell Stemesss

PURPOSE: Dysregulated signaling of nuclear transcription factors vitamin D receptor (VDR) and Forkhead box M1 (FOXM1) play important roles in transformation and tumorigenesis. In this study, we sought to determine whether VDR signaling causally impacted FOXM1 signaling in and pathogenesis of pancrea...

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Bibliografiset tiedot
Julkaisussa:Clin Cancer Res
Päätekijät: LI, ZHIWEI, JIA, ZHILIANG, GAO, YONG, XIE, DACHENG, WEI, DAOYAN, CUI, JIUJIE, MISHRA, LOPA, HUANG, SUYUN, ZHANG, YANQIAO, XIE, KEPING
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334671/
https://ncbi.nlm.nih.gov/pubmed/25501129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2437
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