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Dysregulated KLF4 and Vitamin D Receptor Signaling Promotes Hepatocellular Carcinoma Progression

BACKGROUND & AIMS: Krüppel-like factor 4 (KLF4) is a putative tumor suppressor gene, however, the functional status and significance of KLF4 in hepatocellular carcinogenesis is unknown. In this study, we sought to determine the clinical significance and underlying mechanisms of its dysregulated...

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Detalhes bibliográficos
Main Authors: Li, Qi, Gao, Yong, Jia, Zhiliang, Mishra, Lopa, Guo, Kun, Li, Zhiwei, Le, Xiangdong, Wei, Daoyan, Huang, Suyun, Xie, Keping
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653768/
https://ncbi.nlm.nih.gov/pubmed/22677193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2012.05.043
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