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KLF4α Upregulation Promotes Cell Cycle Progression and Reduces Survival Time of Patients with Pancreatic Cancer

BACKGROUND & AIMS: Krüppel-like factor (KLF)4 is a transcription factor associated with tumor suppression and oncogenesis. KLF4 suppresses pancreatic tumorigenesis by unknown mechanisms; we investigated alterations that might affect KLF4 function and lead to tumor formation. METHODS: We identifi...

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Main Authors: WEI, DAOYAN, WANG, LIWEI, KANAI, MASASHI, JIA, ZHILIANG, LE, XIANGDONG, LI, QIANG, WANG, HUAMIN, XIE, KEPING
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245983/
https://ncbi.nlm.nih.gov/pubmed/20727893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.08.022
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