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Structural analysis of multi-helical RNAs by NMR-SAXS/WAXS: Application to the U4/U6 di-snRNA
NMR and SAXS/WAXS are highly complementary approaches for the analysis of RNA structure in solution. Here we describe an efficient NMR-SAXS/WAXS approach for structural investigation of multi-helical RNAs. We illustrate this approach by determining the overall fold of a 92-nucleotide 3-helix junctio...
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| Publicado no: | J Mol Biol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4790120/ https://ncbi.nlm.nih.gov/pubmed/26655855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.11.026 |
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