Structural requirements for protein-catalyzed annealing of U4 and U6 RNAs during di-snRNP assembly

Base-pairing of U4 and U6 snRNAs during di-snRNP assembly requires large-scale remodeling of RNA structure that is chaperoned by the U6 snRNP protein Prp24. We investigated the mechanism of U4/U6 annealing in vitro using an assay that enables visualization of ribonucleoprotein complexes and faithful...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Didychuk, Allison L., Montemayor, Eric J., Brow, David A., Butcher, Samuel E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2016
Gaiak:
RNA
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756825/
https://ncbi.nlm.nih.gov/pubmed/26673715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1374
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