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Assembly and dynamics of the U4/U6 di-snRNP by single-molecule FRET

In large ribonucleoprotein machines, such as ribosomes and spliceosomes, RNA functions as an assembly scaffold as well as a critical catalytic component. Protein binding to the RNA scaffold can induce structural changes, which in turn modulate subsequent binding of other components. The spliceosomal...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Hardin, John W., Warnasooriya, Chandani, Kondo, Yasushi, Nagai, Kiyoshi, Rueda, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
Soggetti:
RNA
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678811/
https://ncbi.nlm.nih.gov/pubmed/26503251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1011
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