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Structure of the yeast U2/U6 snRNA complex

The U2/U6 snRNA complex is a conserved and essential component of the active spliceosome that interacts with the pre-mRNA substrate and essential protein splicing factors to promote splicing catalysis. Here we have elucidated the solution structure of a 111-nucleotide U2/U6 complex using an approach...

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Autores principales: Burke, Jordan E., Sashital, Dipali G., Zuo, Xiaobing, Wang, Yun-Xing, Butcher, Samuel E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312555/
https://ncbi.nlm.nih.gov/pubmed/22328579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.031138.111
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