Laddar...
Mitochondrial ClpP activity is required for cisplatin resistance in human cells
In human cells ClpP and ClpX are imported into the mitochondrial matrix, where they interact to form the ATP-dependent protease ClpXP and play a role in the mitochondrial unfolded protein response. We find that reducing the levels of mitochondrial ClpP or ClpX renders human cancer cells more sensiti...
Sparad:
| I publikationen: | Biochim Biophys Acta |
|---|---|
| Huvudupphovsmän: | , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2015
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4788106/ https://ncbi.nlm.nih.gov/pubmed/26675528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2015.12.005 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|