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Antibacterial Activity of and Resistance to Small Molecule Inhibitors of the ClpP Peptidase

There is rapidly mounting evidence that intracellular proteases in bacteria are compelling targets for antibacterial drugs. Multiple reports suggest that the human pathogen Mycobacterium tuberculosis and other actinobacteria may be particularly sensitive to small molecules that perturb the activitie...

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Udgivet i:ACS Chem Biol
Main Authors: Compton, Corey L., Schmitz, Karl R., Sauer, Robert T., Sello, Jason K.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287380/
https://ncbi.nlm.nih.gov/pubmed/24047344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400577b
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