Caricamento...
Examination of a Structural Model of Peptidomimicry by Cyclic Acyldepsipeptide Antibiotics in their Interaction with the ClpP Peptidase
The cyclic acyldepsipeptide (ADEP) antibiotics act by binding the ClpP peptidase and dysregulating its activity. Their exocyclic N-acylphenylalanine is thought to structurally mimic the ClpP-binding, (I/L)GF tripeptide loop of the peptidase’s accessory ATPases. We found that ADEP analogs with exocyc...
Salvato in:
| Pubblicato in: | Chembiochem |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4992462/ https://ncbi.nlm.nih.gov/pubmed/26147653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201500234 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|