Načítá se...
Mitochondrial ClpP activity is required for cisplatin resistance in human cells
In human cells ClpP and ClpX are imported into the mitochondrial matrix, where they interact to form the ATP-dependent protease ClpXP and play a role in the mitochondrial unfolded protein response. We find that reducing the levels of mitochondrial ClpP or ClpX renders human cancer cells more sensiti...
Uloženo v:
| Vydáno v: | Biochim Biophys Acta |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2015
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4788106/ https://ncbi.nlm.nih.gov/pubmed/26675528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2015.12.005 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|