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Binding of the ClpA Unfoldase Opens the Axial Gate of ClpP Peptidase

ClpP is a serine protease whose active sites are sequestered in a cavity enclosed between two heptameric rings of subunits. The ability of ClpP to process folded protein substrates depends on its being partnered by an AAA+ ATPase/unfoldase, ClpA or ClpX. In active complexes, substrates are unfolded...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Effantin, Grégory, Maurizi, Michael R., Steven, Alasdair C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863180/
https://ncbi.nlm.nih.gov/pubmed/20236930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.090498
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