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ClpA mediates directional translocation of substrate proteins into the ClpP protease
The intracellular degradation of many proteins is mediated in an ATP-dependent manner by large assemblies comprising a chaperone ring complex associated coaxially with a proteolytic cylinder, e.g., ClpAP, ClpXP, and HslUV in prokaryotes, and the 26S proteasome in eukaryotes. Recent studies of the ch...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The National Academy of Sciences
2001
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC31127/ https://ncbi.nlm.nih.gov/pubmed/11259663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.071043698 |
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