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A Single ClpS Monomer Is Sufficient to Direct the Activity of the ClpA Hexamer
ClpS is an adaptor protein that interacts with ClpA and promotes degradation of proteins with N-end rule degradation motifs (N-degrons) by ClpAP while blocking degradation of substrates with other motifs. Although monomeric ClpS forms a 1:1 complex with an isolated N-domain of ClpA, only one molecul...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2838299/ https://ncbi.nlm.nih.gov/pubmed/20068042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.053736 |
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