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Clock-like mutational processes in human somatic cells
During the course of a lifetime somatic cells acquire mutations. Different mutational processes may contribute to the mutations accumulated in a cell, with each imprinting a mutational signature on the cell’s genome. Some processes generate mutations throughout life at a constant rate in all individ...
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| Veröffentlicht in: | Nat Genet |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4783858/ https://ncbi.nlm.nih.gov/pubmed/26551669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3441 |
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