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Clock-like mutational processes in human somatic cells

During the course of a lifetime somatic cells acquire mutations. Different mutational processes may contribute to the mutations accumulated in a cell, with each imprinting a mutational signature on the cell’s genome. Some processes generate mutations throughout life at a constant rate in all individ...

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Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Alexandrov, Ludmil B., Jones, Philip H., Wedge, David C., Sale, Julian E., Campbell, Peter J., Nik-Zainal, Serena, Stratton, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783858/
https://ncbi.nlm.nih.gov/pubmed/26551669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3441
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