Chronic ethanol feeding promotes azoxymethane and dextran sulfate sodium-induced colonic tumorigenesis potentially by enhancing mucosal inflammation

BACKGROUND: Alcohol consumption is one of the major risk factors for colorectal cancer. However, the mechanism involved in this effect of alcohol is unknown. METHODS: We evaluated the effect of chronic ethanol feeding on azoxymethane and dextran sulfate sodium (AOM/DSS)-induced carcinogenesis in mou...

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Pubblicato in:BMC Cancer
Autori principali: Shukla, Pradeep K., Chaudhry, Kamaljit K., Mir, Hina, Gangwar, Ruchika, Yadav, Nikki, Manda, Bhargavi, Meena, Avtar S., Rao, RadhaKrishna
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782373/
https://ncbi.nlm.nih.gov/pubmed/26951793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2180-x
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