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Calcium-Ask1-MKK7-JNK2-c-Src Signaling Cascade Mediates Disruption of Intestinal Epithelial Tight Junctions by Dextran Sulfate Sodium

Disruption of intestinal epithelial tight junctions is an important event in the pathogenesis of ulcerative colitis. Dextran sodium sulfate (DSS) induces colitis in mice with the symptoms similar to ulcerative colitis. However, the mechanism of DSS-induced colitis is unknown. We investigated the mec...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Samak, Geetha, Chaudhry, Kamaljit K., Gangwar, Ruchika, Narayanan, Damodaran, Jaggar, Jonathan H., Rao, RadhaKrishna
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385020/
https://ncbi.nlm.nih.gov/pubmed/25377781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20140450
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