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A systematic review and economic evaluation of diagnostic strategies for Lynch syndrome.

BACKGROUND: Lynch syndrome (LS) is an inherited autosomal dominant disorder characterised by an increased risk of colorectal cancer (CRC) and other cancers, and caused by mutations in the deoxyribonucleic acid (DNA) mismatch repair genes. OBJECTIVE: To evaluate the accuracy and cost-effectiveness of...

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Dades bibliogràfiques
Publicat a:Health Technol Assess
Autors principals: Snowsill, Tristan, Huxley, Nicola, Hoyle, Martin, Jones-Hughes, Tracey, Coelho, Helen, Cooper, Chris, Frayling, Ian, Hyde, Chris
Format: Artigo
Idioma:Inglês
Publicat: NIHR Journals Library 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4781313/
https://ncbi.nlm.nih.gov/pubmed/25244061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3310/hta18580
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