A systematic review and economic evaluation of diagnostic strategies for Lynch syndrome.

BACKGROUND: Lynch syndrome (LS) is an inherited autosomal dominant disorder characterised by an increased risk of colorectal cancer (CRC) and other cancers, and caused by mutations in the deoxyribonucleic acid (DNA) mismatch repair genes. OBJECTIVE: To evaluate the accuracy and cost-effectiveness of...

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Vydáno v:Health Technol Assess
Hlavní autoři: Snowsill, Tristan, Huxley, Nicola, Hoyle, Martin, Jones-Hughes, Tracey, Coelho, Helen, Cooper, Chris, Frayling, Ian, Hyde, Chris
Médium: Artigo
Jazyk:Inglês
Vydáno: NIHR Journals Library 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4781313/
https://ncbi.nlm.nih.gov/pubmed/25244061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3310/hta18580
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