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A model-based assessment of the cost–utility of strategies to identify Lynch syndrome in early-onset colorectal cancer patients
BACKGROUND: Lynch syndrome is an autosomal dominant cancer predisposition syndrome caused by mutations in the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2. Individuals with Lynch syndrome have an increased risk of colorectal cancer, endometrial cancer, ovarian and other cancers. Lynch syndrom...
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| Publicado no: | BMC Cancer |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4428233/ https://ncbi.nlm.nih.gov/pubmed/25910169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1254-5 |
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