A model-based assessment of the cost–utility of strategies to identify Lynch syndrome in early-onset colorectal cancer patients

BACKGROUND: Lynch syndrome is an autosomal dominant cancer predisposition syndrome caused by mutations in the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2. Individuals with Lynch syndrome have an increased risk of colorectal cancer, endometrial cancer, ovarian and other cancers. Lynch syndrom...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:BMC Cancer
Hauptverfasser: Snowsill, Tristan, Huxley, Nicola, Hoyle, Martin, Jones-Hughes, Tracey, Coelho, Helen, Cooper, Chris, Frayling, Ian, Hyde, Chris
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428233/
https://ncbi.nlm.nih.gov/pubmed/25910169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1254-5
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge