A systematic review and economic evaluation of diagnostic strategies for Lynch syndrome.

BACKGROUND: Lynch syndrome (LS) is an inherited autosomal dominant disorder characterised by an increased risk of colorectal cancer (CRC) and other cancers, and caused by mutations in the deoxyribonucleic acid (DNA) mismatch repair genes. OBJECTIVE: To evaluate the accuracy and cost-effectiveness of...

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Detalhes bibliográficos
Publicado no:Health Technol Assess
Main Authors: Snowsill, Tristan, Huxley, Nicola, Hoyle, Martin, Jones-Hughes, Tracey, Coelho, Helen, Cooper, Chris, Frayling, Ian, Hyde, Chris
Formato: Artigo
Idioma:Inglês
Publicado em: NIHR Journals Library 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4781313/
https://ncbi.nlm.nih.gov/pubmed/25244061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3310/hta18580
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