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Targeting the JMJD2 Histone Demethylases to Epigenetically Control Herpesvirus Infection and Reactivation from Latency

Chromatin and the chromatin modulation machinery not only provide a regulatory matrix for enabling cellular functions such as DNA replication and transcription but also regulate the infectious cycles of many DNA viruses. Elucidation of the components and mechanisms involved in this regulation is pro...

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Détails bibliographiques
Publié dans:Sci Transl Med
Auteurs principaux: Liang, Yu, Vogel, Jodi L., Arbuckle, Jesse H., Rai, Ganesha, Jadhav, Ajit, Simeonov, Anton, Maloney, David J., Kristie, Thomas M.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778723/
https://ncbi.nlm.nih.gov/pubmed/23303604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3005145
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