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Targeting the JMJD2 Histone Demethylases to Epigenetically Control Herpesvirus Infection and Reactivation from Latency

Chromatin and the chromatin modulation machinery not only provide a regulatory matrix for enabling cellular functions such as DNA replication and transcription but also regulate the infectious cycles of many DNA viruses. Elucidation of the components and mechanisms involved in this regulation is pro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Transl Med
Hauptverfasser: Liang, Yu, Vogel, Jodi L., Arbuckle, Jesse H., Rai, Ganesha, Jadhav, Ajit, Simeonov, Anton, Maloney, David J., Kristie, Thomas M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778723/
https://ncbi.nlm.nih.gov/pubmed/23303604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3005145
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