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Targeting the JMJD2 Histone Demethylases to Epigenetically Control Herpesvirus Infection and Reactivation from Latency

Chromatin and the chromatin modulation machinery not only provide a regulatory matrix for enabling cellular functions such as DNA replication and transcription but also regulate the infectious cycles of many DNA viruses. Elucidation of the components and mechanisms involved in this regulation is pro...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Liang, Yu, Vogel, Jodi L., Arbuckle, Jesse H., Rai, Ganesha, Jadhav, Ajit, Simeonov, Anton, Maloney, David J., Kristie, Thomas M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778723/
https://ncbi.nlm.nih.gov/pubmed/23303604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3005145
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