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A Miniaturized Screen for Inhibitors of Jumonji Histone Demethylases
2-Oxoglutarate and Fe(II) dependent oxygenases are a major class of N(ε)-methyl lysine demethylases that are involved in epigenetic regulation. Assays suitable for implementation in a high-throughput manner have been lacking for these enzymes. Here, we describe the design and implementation of a rob...
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| Hoofdauteurs: | , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2009
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3401096/ https://ncbi.nlm.nih.gov/pubmed/20094655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b912993f |
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