Wordt geladen...

A Miniaturized Screen for Inhibitors of Jumonji Histone Demethylases

2-Oxoglutarate and Fe(II) dependent oxygenases are a major class of N(ε)-methyl lysine demethylases that are involved in epigenetic regulation. Assays suitable for implementation in a high-throughput manner have been lacking for these enzymes. Here, we describe the design and implementation of a rob...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Sakurai, Masaaki, Rose, Nathan R., Schultz, Lena, Quinn, Amy, Jadhav, Ajit, Ng, Stanley S., Oppermann, Udo, Schofield, Christopher J., Simeonov, Anton
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401096/
https://ncbi.nlm.nih.gov/pubmed/20094655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b912993f
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!