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Cytoplasmic isoforms of Kaposi sarcoma herpesvirus LANA recruit and antagonize the innate immune DNA sensor cGAS

The latency-associated nuclear antigen (LANA) of Kaposi sarcoma herpesvirus (KSHV) is mainly localized and functions in the nucleus of latently infected cells, playing a pivotal role in the replication and maintenance of latent viral episomal DNA. In addition, N-terminally truncated cytoplasmic isof...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Zhang, Guigen, Chan, Baca, Samarina, Naira, Abere, Bizunesh, Weidner-Glunde, Magdalena, Buch, Anna, Pich, Andreas, Brinkmann, Melanie M., Schulz, Thomas F.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776510/
https://ncbi.nlm.nih.gov/pubmed/26811480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516812113
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